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Latest study results: How CBD can affect blood pressure
In a recent study published in the Journal of Biomedicine and Pharmacotherapy, scientists investigated how cannabidiol (CBD) affects blood pressure and vascular function in people with primary hypertension. The researchers conducted a randomized crossover study, the results of which are summarized below.
High blood pressure: A widespread problem
High blood pressure, also known as hypertension, occurs when the blood pressure in the arteries is permanently above 140/90 mmHg. According to a study by the Robert Koch Institute, which included 24,016 people, almost a third of the German population suffers from this disease. Hypertension is one of the main factors that increase the risk of cardiovascular disease. Various causes play a role, such as:
hereditary predisposition
Old
Gender
Unhealthy lifestyle and diet
There are two main forms: primary or essential hypertension, the exact cause of which is unknown, and secondary hypertension, which is caused by other diseases. Around 90% of those affected have the primary form. The question investigated in this study was whether CBD has an effect on blood pressure and vascular function in people with essential hypertension.
course of study
The randomized, placebo-controlled study was conducted at the University of Split from December 2021 to April 2022. Participants were people aged 40 to 70 years with diagnosed primary hypertension and a BMI between 18.5 and 35 kg/m².
Excluded were smokers, people with secondary hypertension and those taking medications other than ACE inhibitors, diuretics or calcium channel blockers to lower blood pressure. Over the course of the study, CBD intake was continuously monitored to analyze possible effects on blood pressure and urotensin-II (U-II), a protein associated with high blood pressure and atherosclerosis. The subjects took CBD for five weeks to observe changes in their blood values.
results of the study
After the five-week period, there was a significant reduction in U-II levels in the blood as well as a decrease in average blood pressure over 24 hours. The researchers found that the reduction in blood pressure was directly related to the reduction in U-II.
The most important findings from the study are:
Long-term use of CBD can lower both U-II levels and 24-hour blood pressure.
These effects occurred regardless of the participants’ age, gender and BMI.
conclusion of the scientists
The effects of CBD on blood pressure have been the subject of several studies, and there is evidence that CBD can positively influence blood flow in stressful situations. This study also showed a clear link between CBD intake and a reduction in blood pressure, which is partly explained by the reduction in U-II. However, further studies are needed to fully understand the exact mechanisms of action of CBD on blood pressure.
What should I pay attention to?
There are a few important points to consider when purchasing an effective CBD oil. First, users should know that the market is currently not strictly regulated, which can lead to significant differences in the quality of products. Therefore, look for a trusted brand that publishes lab results to confirm the exact CBD concentration and purity of the product.
Another consideration is the type of product: is it full-spectrum, broad-spectrum, or CBD isolate? Full-spectrum CBD oils contain other cannabinoids and terpenes in addition to CBD, including small, legal amounts of THC. Since THC may be able to lower blood pressure, this option could be particularly beneficial.
Additionally, you should consider the overall quality of the CBD oil. Factors such as where the hemp is grown, whether it is organic, the extraction process used, and other details all play a role. Reviews from previous customers on the internet can also be helpful in getting an idea of the company's reliability.
We hope this article was useful for you, but before using CBD oil for high blood pressure or any other condition, be sure to consult a doctor.
studies and sources
Mancia G, Fagard R, Narkiewicz K, Redon J, Zanchetti A, Bohm M et al. (2013) ESH/ESC Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertension, 31(7):1281-357
Robert Koch Institute (2017). 12-month prevalence of hypertension in Germany. Journal of Health Monitoring.
Ebata et al., (2020). Birth Weight Standard Deviation Score is a Significant Determinant of Serum Urotensin-II Levels at Term-Equivalent Age in Preterm Infants. Download June 27, 2022, from [Source]
] Kumric, M. et al. (2023). Effects of CBD supplementation on ambulatory blood pressure and serum urotensin II concentrations in Caucasian patients with essential hypertension: A sub-analysis of the HYPER-H21-4 trial. Biomedicine and Pharmacotherapy. Download June 27, 2023, from [source]
For legal reasons, we would like to point out that the effects of hemp and cannabinoids (CBD) described here refer exclusively to public scientific reports and specialist reports, publications and user experiences and are not to be understood as instructions for use or promises of healing. The text is in no way a substitute for professional advice from a doctor and may not be used as a basis for independent diagnosis and the start, change or termination of treatment of diseases. Always consult your trusted doctor if you have any health questions or complaints!
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